iRegulon

Sequence-based Discovery of Regulons.

iRegulon detects the TF, the targets and the motifs/tracks from a set of genes.

INFO! The new version of iRegulon is also available for Cytoscape 3. More info >>
INFO! iRegulon paper is now published and available. More info >>
View description Tutorial Download

Application Examples

Detect regulons from co-expressed genes

iRegulon detects the master regulons and co-factors from a set of differentially expressed genes.

Learn more »

Detect regulons and co-factors from ChIP-derived targets

iRegulon detects the master regulons and co-factors from a set of genes derived from ChIP-seq data.

Learn more »

Predict metatargetomes

For a given TF, iRegulon predicts the metatargetome over thousands of published gene signatures.

Learn more »

Detect direct regulations in pathways

For a given cluster of functionnally related genes, iRegulon identifies the direct TF-target interactions.

Learn more »

Predict TF-miRNA co-regulations

When applied to miRNA targets, iRegulon reveals cross-talks between TF and miRNA regulons.

Learn more »